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1

The molecular mechanisms of transition between mesenchymal and amoeboid invasiveness in tumor cells

K. Paňková, D. Rösel, M. Novotný, Jan Brábek

Journal:

Cellular and Molecular Life Sciences

Year:

2010

Language:

english

File:

PDF, 242 KB

english, 2010

2

Vimentin Intermediate Filaments as Potential Target for Cancer Treatment

Strouhalova, Katerina, Přechová, Magdalena, Gandalovičová, Aneta, Brábek, Jan, Gregor, Martin, Rosel, Daniel

Journal:

Year:

2020

Language:

english

File:

PDF, 993 KB

english, 2020

3

Src transformation of colonic epithelial cells: Enhanced anchorage-independent growth in an Apc+/min background

Sabata S. Constancio-Lund, Jan Brabek, Steven K. Hanks

Journal:

Molecular Carcinogenesis

Year:

2009

Language:

english

File:

PDF, 312 KB

english, 2009

4

The role of the tissue microenvironment in the regulation of cancer cell motility and invasion

Jan Brábek, Claudia T Mierke, Daniel Rösel, Pavel Veselý, Ben Fabry

Journal:

Cell Communication and Signaling

Year:

2010

Language:

english

File:

PDF, 711 KB

english, 2010

5

Confocal microscopy reveals Myzitiras and Vthela morphotypes as new signatures of malignancy progression

Pavel Veselý, Daniel Rösel, Daniela Paňková, Ondřej Tolde, Chris Blase, Eva Matoušková, Petr Folk, Jan Brábek, Juergen Bereiter-Hahn

Journal:

Year:

2009

Language:

english

File:

PDF, 193 KB

english, 2009

6

Etiologic and causative factors in perianal dermatitis: results of a prospective study in 126 patients

Birger Kränke, Michaela Trummer, Eva Brabek, Peter Komericki, Theo Dieter Turek, Werner Aberer

Journal:

Wiener klinische Wochenschrift

Year:

2006

File:

PDF, 155 KB

2006

7

CAS promotes invasiveness of Src-transformed cells

Brábek, Jan, Constancio, Sábata S, Shin, Nah-Young, Pozzi, Ambra, Weaver, Alissa M, Hanks, Steven K

Journal:

Year:

2004

Language:

english

File:

PDF, 321 KB

english, 2004

8

Regulation and localization of CAS substrate domain tyrosine phosphorylation

Priscila M. Fonseca, Nah-Young Shin, Jan Brábek, Larisa Ryzhova, Jiong Wu, Steven K. Hanks

Journal:

Cellular Signalling

Year:

2004

Language:

english

File:

PDF, 463 KB

english, 2004

9

Contractile forces in tumor cell migration

Claudia Tanja Mierke, Daniel Rösel, Ben Fabry, Jan Brábek

Journal:

European Journal of Cell Biology

Year:

2008

Language:

english

File:

PDF, 754 KB

english, 2008

10

The structure of invadopodia in a complex 3D environment

Ondřej Tolde, Daniel Rösel, Pavel Veselý, Petr Folk, Jan Brábek

Journal:

European Journal of Cell Biology

Year:

2010

Language:

english

File:

PDF, 3.30 MB

english, 2010

11

The Fission Yeast Ortholog of the Coregulator SKIP Interacts with the Small Subunit of U2AF

Monika Ambrozková, František Půta, Iva Fuková, Michal Skružný, Jan Brábek, Petr Folk

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 251 KB

english, 2001

12

The SH3 domain of Src can downregulate its kinase activity in the absence of the SH2 domain-pY527 interaction

Jan Brábek, Dominik Mojžita, Marian Novotný, František Pu̇ta, Petr Folk

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 268 KB

english, 2002

13

Anaphylactic shock following peritumoral injection of patent blue in sentinel lymph node biopsy procedure

I. Woltsche-Kahr, P. Komericki, B. Kränke, E. Brabek, M. Horn, S. Schuller-Petrovic, E. Richtig, W. Aberer

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2000

Language:

english

File:

PDF, 114 KB

english, 2000

14

NG2-mediated Rho activation promotes amoeboid invasiveness of cancer cells

Daniela Paňková, Njainday Jobe, Magdalena Kratochvílová, Roberto Buccione, Jan Brábek, Daniel Rösel

Journal:

European Journal of Cell Biology

Year:

2012

Language:

english

File:

PDF, 1.17 MB

english, 2012

15

S.P.47 CARE-NMD: Evaluation and implementation of relevant health related QoL instruments in Duchenne muscular dystrophy

Rahbek, J., Højberg, A., Mahoney, A., Steffensen, B., Rodger, S., Bushby, K., Lochmüller, H., Gramsch, K., Vry, J., Kirschner, J., Antonova, V., Brabek, P., Guergueltcheva, V., Karcagi, V., Herczegfal

Journal:

Neuromuscular Disorders

Year:

2012

Language:

english

File:

PDF, 49 KB

english, 2012

16

Affordable cancer care

Jan Brábek, Michael Fernandes

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 41 KB

english, 2012

17

Metastasis of aggressive amoeboid sarcoma cells is dependent on Rho/ROCK/MLC signaling

Jan Kosla, Daniela Paňková, Jiří Plachý, Ondřej Tolde, Kristýna Bicanová, Michal Dvořák, Daniel Rösel, Jan Brábek

Journal:

Cell Communication and Signaling

Year:

2013

Language:

english

File:

PDF, 2.36 MB

english, 2013

18

CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics

Janoštiak, Radoslav, Brábek, Jan, Auernheimer, Vera, Tatárová, Zuzana, Lautscham, Lena A., Dey, Tuli, Gemperle, Jakub, Merkel, Rudolf, Goldmann, Wolfgang H., Fabry, Ben, Rösel, Daniel

Journal:

Cellular and Molecular Life Sciences

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

19

Translation in solid cancer: are size‐based response criteria an anachronism?

Fernandes, M., Rosel, D., Brábek, J.

Journal:

Clinical and Translational Oncology

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

20

Mechanosensors in integrin signaling: The emerging role of p130Cas

Janoštiak, Radoslav, Pataki, Andreea Csilla, Brábek, Jan, Rösel, Daniel

Journal:

European Journal of Cell Biology

Year:

2014

Language:

english

File:

PDF, 2.02 MB

english, 2014

21

Up-Regulation of Rho/ROCK Signaling in Sarcoma Cells Drives Invasion and Increased Generation of Protrusive Forces

Rosel, D., Brabek, J., Tolde, O., Mierke, C. T., Zitterbart, D. P., Raupach, C., Bicanova, K., Kollmannsberger, P., Pankova, D., Vesely, P., Folk, P., Fabry, B.

Journal:

Molecular Cancer Research

Year:

2008

Language:

english

File:

PDF, 733 KB

english, 2008

22

Tyrosine phosphorylation within the SH3 domain regulates CAS subcellular localization, cell migration, and invasiveness

Janostiak, R., Tolde, O., Bruhova, Z., Novotny, M., Hanks, S. K., Rosel, D., Brabek, J.

Journal:

Molecular Biology of the Cell

Year:

2011

Language:

english

File:

PDF, 1.70 MB

english, 2011

23

Wnt Signaling Cascades and the Roles of Syndecan Proteoglycans

Pataki, C. A., Couchman, J. R., Brabek, J.

Journal:

Journal of Histochemistry & Cytochemistry

Year:

2015

Language:

english

File:

PDF, 1.94 MB

english, 2015

24

Crk-Associated Substrate Tyrosine Phosphorylation Sites Are Critical for Invasion and Metastasis of Src-Transformed Cells

Journal:

Molecular Cancer Research

Year:

2005

Language:

english

File:

PDF, 391 KB

english, 2005

25

PKCα promotes the mesenchymal to amoeboid transition and increases cancer cell invasiveness

Vaškovičová, Katarína, Szabadosová, Emilia, Čermák, Vladimír, Gandalovičová, Aneta, Kasalová, Lenka, Rösel, Daniel, Brábek, Jan

Journal:

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

26

Multilokuläre fixe Arzneireaktion unter dem Bild einer Intertrigo bei einem Diabetiker

E. Brabek, B. Kränke

Year:

2000

File:

PDF, 97 KB

2000

27

Simultaneous blocking of IL-6 and IL-8 is sufficient to fully inhibit CAF-induced human melanoma cell invasiveness

Jobe, Njainday Pulo, Rösel, Daniel, Dvořánková, Barbora, Kodet, Ondřej, Lacina, Lukáš, Mateu, Rosana, Smetana, Karel, Brábek, Jan

Journal:

Histochemistry and Cell Biology

Year:

2016

Language:

english

File:

PDF, 2.88 MB

english, 2016

28

ROCK Inhibitors as Emerging Therapeutic Candidates for Sarcomas

Micuda, S., Rosel, D., Ryska, A., Brabek, J.

Journal:

Current Cancer Drug Targets

Year:

2010

Language:

english

File:

PDF, 240 KB

english, 2010

29

The role of focal adhesion anchoring domains of CAS in mechanotransduction

Braniš, Jaroslav, Pataki, Csilla, Spörrer, Marina, Gerum, Richard C., Mainka, Astrid, Cermak, Vladimir, Goldmann, Wolfgang H., Fabry, Ben, Brabek, Jan, Rosel, Daniel

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.30 MB

english, 2017

30

ARHGAP42 is activated by Src–mediated tyrosine phosphorylation to promote cell motility

Luo, Weifeng, Janoštiak, Radoslav, Tolde, Ondřej, Ryzhova, Larisa M., Koudelková, Lenka, Dibus, Michal, Brábek, Jan, Hanks, Steven K., Rosel, Daniel

Journal:

Journal of Cell Science

Year:

2017

Language:

english

File:

PDF, 3.93 MB

english, 2017

31

Migrastatics—Anti-metastatic and Anti-invasion Drugs: Promises and Challenges

Gandalovičová, Aneta, Rosel, Daniel, Fernandes, Michael, Veselý, Pavel, Heneberg, Petr, Čermák, Vladimír, Petruželka, Luboš, Kumar, Sunil, Sanz-Moreno, Victoria, Brábek, Jan

Journal:

Trends in Cancer

Year:

2017

Language:

english

File:

PDF, 2.95 MB

english, 2017

32

Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners

Gemperle, Jakub, Hexnerová, Rozálie, Lepšík, Martin, Tesina, Petr, Dibus, Michal, Novotný, Marian, Brábek, Jan, Veverka, Václav, Rosel, Daniel

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 5.81 MB

english, 2017

33

Cancer, checkpoint inhibitors, and confusion

Fernandes, Michael, Brábek, Jan

Journal:

The Lancet Oncology

Year:

2017

Language:

english

File:

PDF, 37 KB

english, 2017

34

Acne excoriata – Look for Allergy!

Kränke, Birger, Brabek, Eva, Derhaschnig, Johann, Aberer, Werner

Journal:

Year:

2001

Language:

english

File:

PDF, 100 KB

english, 2001

35

Fibroblasts potentiate melanoma cells in vitro invasiveness induced by UV-irradiated keratinocytes

Jobe, Njainday Pulo, Živicová, Veronika, Mifková, Alžběta, Rösel, Daniel, Dvořánková, Barbora, Kodet, Ondřej, Strnad, Hynek, Kolář, Michal, Šedo, Aleksi, Smetana, Karel, Strnadová, Karolina, Brábek, J

Journal:

Histochemistry and Cell Biology

Year:

2018

Language:

english

File:

PDF, 2.06 MB

english, 2018

36

Neoplastic progression of the human breast cancer cell line G3S1 is associated with elevation of cytoskeletal dynamics and upregulation of MT1-MMP

Journal:

International Journal of Oncology

Year:

2010

Language:

english

File:

PDF, 737 KB

english, 2010

37

Pragmatic medicine in solid cancer: a translational alternative to precision medicine

Brabek, Jan, Rosel, Daniel, Fernandes, Michael

Journal:

OncoTargets and Therapy

Year:

2016

Language:

english

File:

PDF, 2.03 MB

english, 2016

38

Drugs for solid cancer the productivity crisis prompts a rethink

Brabek, Jan, Rösel,, Veselý,, Fernandes, Mike

Journal:

OncoTargets and Therapy

Year:

2013

Language:

english

File:

PDF, 2.15 MB

english, 2013

39

Quantitative phase imaging unravels new insight into dynamics of mesenchymal and amoeboid cancer cell invasion

Tolde, Ondřej, Gandalovičová, Aneta, Křížová, Aneta, Veselý, Pavel, Chmelík, Radim, Rosel, Daniel, Brábek, Jan

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.61 MB

english, 2018

40

The interaction of p130Cas with PKN3 promotes malignant growth

Gemperle, Jakub, Dibus, Michal, Koudelková, Lenka, Rosel, Daniel, Brábek, Jan

Journal:

Molecular Oncology

Year:

2018

Language:

english

File:

PDF, 3.18 MB

english, 2018

41

Novel FRET-Based Src Biosensor Reveals Mechanisms of Src Activation and Its Dynamics in Focal Adhesions

Koudelková, Lenka, Pataki, Andreea Csilla, Tolde, Ondřej, Pavlik, Vojtech, Nobis, Max, Gemperle, Jakub, Anderson, Kurt, Brábek, Jan, Rosel, Daniel

Journal:

Cell Chemical Biology

Year:

2018

Language:

english

File:

PDF, 4.65 MB

english, 2018

42

Solid cancer: the new tumour spread endpoint opens novel opportunities

Fernandes, Michael, Rosel, Daniel, Brábek, Jan

Journal:

British Journal of Cancer

Year:

2019

File:

PDF, 280 KB

2019

43

Migrastatics: Redirecting R&D in Solid Cancer Towards Metastasis?

Rosel, Daniel, Fernandes, Michael, Sanz-Moreno, Victoria, Brábek, Jan

Journal:

Trends in Cancer

Year:

2019

Language:

english

File:

PDF, 359 KB

english, 2019

44

ChemInform Abstract: UEBERGANGSMETALLKOMPLEXE MIT N-HALTIGEN LIGANDEN 2. MITT. KOORDINATIONSVERBINDUNGEN DES TYPS C5H5MN(CO)2L MIT ORGANISCHEN NITRILEN 3. MITT. DONATOR-AKZEPTOR-EIGENSCHAFTEN ORGANISCHER NITRILE IM SYST. C5H5MN(CO)2L

HERBERHOLD, MAX, BRABEK, HARTMUT

Journal:

Chemischer Informationsdienst. Organische Chemie

Year:

1971

Language:

german

File:

PDF, 178 KB

german, 1971

45

Migrastatics: Redirecting R&D in Solid Cancer Towards Metastasis?

Rosel, Daniel, Fernandes, Michael, Sanz-Moreno, Victoria, Brábek, Jan

Journal:

Trends in Cancer

Year:

2019

File:

PDF, 359 KB

2019

46

ChemInform Abstract: UEBERGANGSMETALLKOMPLEXE MIT N-HALTIGEN LIGANDEN 2. MITT. KOORDINATIONSVERBINDUNGEN DES TYPS C5H5MN(CO)2L MIT ORGANISCHEN NITRILEN 3. MITT. DONATOR-AKZEPTOR-EIGENSCHAFTEN ORGANISCHER NITRILE IM SYST. C5H5MN(CO)2L

HERBERHOLD, MAX, BRABEK, HARTMUT

Journal:

Chemischer Informationsdienst. Organische Chemie

Year:

1971

File:

PDF, 178 KB

1971